1,641 research outputs found
IRAS 19135+3937: An SRd variable as interacting binary surrounded by a circumbinary disc
Semi-regular (SR) variables are not a homogeneous class and their variability
is often explained due to pulsations and/or binarity. This study focuses on
IRAS 19135+3937, an SRd variable with an infra-red excess indicative of a dusty
disc. A time-series of high-resolution spectra, UBV photometry as well as a
very accurate light curve obtained by the Kepler satellite, allowed us to study
the object in unprecedented detail. We discovered it to be a binary with a
period of 127 days. The primary has a low surface gravity and an atmosphere
depleted in refractory elements. This combination of properties unambiguously
places IRAS 19135+3937 in the subclass of post-Asymptotic Giant Branch stars
with dusty discs.
We show that the light variations in this object can not be due to
pulsations, but are likely caused by the obscuration of the primary by the
circumbinary disc during orbital motion. Furthermore, we argue that the
double-peaked Fe emission lines provide evidence for the existence of a gaseous
circumbinary Keplerian disc inside the dusty disc. A secondary set of
absorption lines has been detected near light minimum, which we attribute to
the reflected spectrum of the primary on the disc wall, which segregates due to
the different Doppler shift. This corroborates the recent finding that
reflection in the optical by this type of discs is very efficient. The system
also shows a variable Halpha profile indicating a collimated outflow
originating around the companion. IRAS 19135+3937 thus encompasses all the
major emergent trends about evolved disc systems, that will eventually help to
place these objects in the evolutionary context.Comment: Accepted to MNRA
Hysteresis and bi-stability by an interplay of calcium oscillations and action potential firing
Many cell types exhibit oscillatory activity, such as repetitive action
potential firing due to the Hodgkin-Huxley dynamics of ion channels in the cell
membrane or reveal intracellular inositol triphosphate (IP) mediated
calcium oscillations (CaOs) by calcium-induced calcium release channels
(IP-receptor) in the membrane of the endoplasmic reticulum (ER). The
dynamics of the excitable membrane and that of the IP-mediated CaOs have
been the subject of many studies. However, the interaction between the
excitable cell membrane and IP-mediated CaOs, which are coupled by
cytosolic calcium which affects the dynamics of both, has not been studied.
This study for the first time applied stability analysis to investigate the
dynamic behavior of a model, which includes both an excitable membrane and an
intracellular IP-mediated calcium oscillator. Taking the IP
concentration as a control parameter, the model exhibits a novel rich spectrum
of stable and unstable states with hysteresis. The four stable states of the
model correspond in detail to previously reported growth-state dependent states
of the membrane potential of normal rat kidney fibroblasts in cell culture. The
hysteresis is most pronounced for experimentally observed parameter values of
the model, suggesting a functional importance of hysteresis. This study shows
that the four growth-dependent cell states may not reflect the behavior of
cells that have differentiated into different cell types with different
properties, but simply reflect four different states of a single cell type,
that is characterized by a single model.Comment: 29 pages, 6 figure
Dirac-Born-Infeld-Volkov-Akulov and deformation of supersymmetry
We deform the action and the supersymmetry transformations of the d = 10 and d = 4 Maxwell supermultiplets so that at each order of the deformation the theory has 16 Maxwell multiplet deformed supersymmetries as well as 16 Volkov-Akulov type non-linear supersymmetries. The result agrees with the expansion in the string tension of the explicit action of the Dirac-Born-Infeld model and its supersymmetries, extracted from D9 and D3 superbranes, respectively. The half-maximal Dirac-Born-Infeld models with 8 Maxwell supermultiplet deformed supersymmetries and 8 Volkov-Akulov type supersymmetries are described by a new class of d = 6 vector branes related to chiral (2,0) supergravity, which we denote as 'Vp-branes'. We use a space-filling V5 superbrane for the d = 6 model and a V3 superbrane for the d = 4 half-maximal Dirac-Born-Infeld (DBI) models. In this way we present a completion to all orders of the deformation of the Maxwell supermultiplets with maximal 16+16 supersymmetries in d = 10 and 4, and half-maximal 8+8 supersymmetries in d = 6 and 4.</p
TLR3, TLR4 and TLRs7-9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma
Defective Rhinovirus induced interferon-β and interferon-λ production has been reported in bronchial epithelial cells from asthmatics but the mechanisms of defective interferon induction in asthma are unknown. Virus infection can induce interferon through Toll like Receptors (TLR)3, TLR7 and TLR8. The role of these TLRs in interferon induction in asthma is unclear. This objective of this study was to measure the type I and III interferon response to TLR in bronchial epithelial cells and peripheral blood cells from atopic asthmatics and non-atopic non-asthmatics. Bronchial epithelial cells and peripheral blood mononuclear cells from atopic asthmatic and non-atopic non-asthmatic subjects were stimulated with agonists to TLR3, TLR4 & TLRs7-9 and type I and III interferon and pro-inflammatory cytokine, interleukin(IL)-6 and IL-8, responses assessed. mRNA expression was analysed by qPCR. Interferon proteins were analysed by ELISA. Pro-inflammatory cytokines were induced by each TLR ligand in both cell types. Ligands to TLR3 and TLR7/8, but not other TLRs, induced interferon-β and interferon-λ in bronchial epithelial cells. The ligand to TLR7/8, but not those to other TLRs, induced only type I interferons in peripheral blood mononuclear cells. No difference was observed in TLR induced interferon or pro-inflammatory cytokine production between asthmatic and non-asthmatic subjects from either cell type. TLR3 and TLR7/8,, stimulation induced interferon in bronchial epithelial cells and peripheral blood mononuclear cells. Interferon induction to TLR agonists was not observed to be different in asthmatics and non-asthmatics
Topological defects and shape of aromatic self-assembled vesicles
We show that the stacking of flat aromatic molecules on a curved surface
results in topological defects. We consider, as an example, spherical vesicles,
self-assembled from molecules with 5- and 6-thiophene cores. We predict that
the symmetry of the molecules influences the number of topological defects and
the resulting equilibrium shape.Comment: accepted as a Letter in the J. Phys. Chem.
Effect of substrate conditions on the plasma beam deposition of amorphous hydrogenated carbon
A study on the effect of substrate conditions was performed for the plasma beam deposition of amorphous hydrogenated carbon ( a -C:H) from an expanding thermal argon/acetylene plasma on glass and crystalline silicon. A new substrate holder was designed, which allows the control of the substrate temperature independent of the plasma settings with an accuracy of 2 K. This is obtained via a combination of a good control of the holder’s yoke temperature and the injection of helium gas between thermally ill connected parts of the substrate holder system. It is demonstrated that the substrate temperature influences both the a -C:H material quality and the deposition rate. The deposition rate and substrate temperature are presented as the two parameters which determine the material quality. In situ studies prove that the deposition process is constant in time and that thermally activated etching processes are unlikely to contribute significantly during deposition. Preliminary experiments with an additional substrate bias reveal that an energetic ion bombardment of the growingfilm surface does not influence the deposition process. A tentative deposition model is proposed based on the creation and destruction of active sites, which depend on the particle fluxes towards the substrate and the substrate temperature. This model allows the qualitative explanation of the observed deposition results
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